Medicinal mishap: Proton pump inhibitor-associated hypomagnesaemia and hypocalcaemia
نویسندگان
چکیده
منابع مشابه
Proton pump inhibitor-induced hypomagnesaemia and hypocalcaemia: case review.
Proton pump inhibitor (PPI)-induced hypomagnesaemia is a rare but serious adverse effect of a widely prescribed medication. It has become an increasingly recognised complication since 2006, with the U.S. Food and Drug Administration issuing a warning for this risk with regards to long-term PPI use. We present the case of PPI-associated hypomagnesaemia and hypocalcaemia. A 91 year old male prese...
متن کاملHypomagnesaemia associated with long-term use of proton pump inhibitors
Hypomagnesaemia and associated hypocalcaemia and hypoparathyroidism have been increasingly recognised as rare long-term side-effects of proton pump inhibitors (PPIs). The PPIs may inhibit active magnesium (Mg) absorption by interfering with transcellular transient receptor potential melastatin-6 and -7 (TRPM 6 and 7) channels. More recent cell culture studies have suggested concomitant inhibiti...
متن کاملHypomagnesaemia with Secondary Hypocalcaemia
In 1965, Paunier et al. described a child of 6 weeks who had generalized convulsions and tetany, associated with low serum magnesium and calcium levels. Magnesium therapy stopped the tetany and established a normal serum calcium level. Similar cases were later reported by Salet et al. (1966), Friedman, Hatcher, and Watson (1967), and Skyberg et al. (1967). Most of these authors suggested that t...
متن کاملProton Pump Inhibitor-associated Mucosal Change
Recently, proton pump inhibitors (PPIs) have been widely used as the first-line treatment for acid-related diseases such as gastroesophageal reflux disease (GERD), gastric ulcers and duodenal ulcers. The number of PPI users has been increasing throughout the world. The suppression of gastric acid by the long-term use of PPIs is suggested to be associated with a number of disorders, including co...
متن کاملHypomagnesemia associated with a proton pump inhibitor.
Severe hypomagnesemia is a serious clinical condition. Proton pump inhibitor (PPI) induced hypomagnesemia has been recognized since 2006. In March 2011 the U.S. Food and Drug Administration advised that long-term use of PPI can induce hypomagnesemia. We report the first Japanese case of hypomagnesemia associated with chronic use of PPIs in a 64-year-old man hospitalized for nausea, bilateral an...
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ژورنال
عنوان ژورنال: Australian Prescriber
سال: 2017
ISSN: 1839-3942
DOI: 10.18773/austprescr.2017.019